• White House Budget Plan Shows Some Investment but Inadequate Commitment to Sustained Public Health R

    The president’s fiscal year 2020 budget proposal released Monday is responsive to some of our nation’s most urgent public health challenges.
  • Ebola Hearing Highlights Global Health Investment Payoffs, Ongoing Needs

    The Senate Appropriations Labor, Health and Human Services Subcommittee’s hearing on the continuing Ebola epidemic in the Democratic Republic of Congo brought the unprecedented challenges posed by the current outbreak, as well as the responses needed before policymakers Thursday.
  • This year’s flu vaccine is doing well, but deaths are still high

    This season’s flu vaccine reduces the need to go to the doctor’s office by about half, according to figures released Thursday.
  • No Effect of IDU on Postoperative Mortality in Infective Endocarditis

    Early postoperative mortality may not differ between infective endocarditis caused by injection drug use (IDU) and non-IDU causes, despite different preoperative clinical characteristics, according to a study published in Clinical Infectious Diseases.
  • Health experts want Texas to eliminate opting out of vaccinations for non-medical reasons

    As the Houston area learns of its sixth possible case of measles in less than two weeks, doctors and scientists are pushing for the Texas Legislature to eliminate the ability for most parents to opt out of vaccines for their children.
  • Risky Antibiotics Still Widely Prescribed at Hospital Discharge

    Hospital-based stewardship programs designed to reduce the rate of Clostridium difficileinfections and antibiotic-related adverse events were associated with reduced use of fluoroquinolone antibiotics during hospitalization, but not at hospital discharge, researchers reported.
  • Restrictive OPAT Criteria for Infective Endocarditis May Need Revision

    Criteria less restrictive than those proposed by the Infectious Diseases Society of America (IDSA) for the use of outpatient parenteral antibiotic treatment (OPAT) for patients with infective endocarditis were found to be efficacious and safe, according to results published in Clinical Infectious Diseases.
  • Pneumococcal Sepsis Risk Remains High in Children After Vaccination

    The incidence of pneumococcal sepsis in children remained high after the introduction of the pneumococcal conjugate vaccine (PCV)-13 in Switzerland, according to a study published in Clinical Infectious Diseases.
  • Williamson sees spike in unvaccinated kids as parents falsely use religious exemption

    Williamson County has seen the number of unvaccinated students entering the district spike significantly in the last year as more parents request religious exemptions to state immunization rules.
  • 24-Hour Flu Pill May Not Be Miracle Drug Doctors Thought

    A new pill that can kill the flu virus in 24 hours with a single dose has become the most-prescribed influenza treatment in Japan, which is suffering through its worst flu season in two decades.
  • Prior dengue infection may protect against Zika: study

    Prior infection with dengue, a mosquito-borne disease that infects nearly 400 million people a year, could reduce the risk of contracting Zika nearly by half, U.S. and Brazilian researchers reported on Thursday.
  • Chickenpox Vaccination and Risk for Herpes Zoster

    The chickenpox vaccination may not have a substantial population-level effect on herpes zoster in nonvaccinated age groups, according to a study published in Clinical Infectious Diseases.
  • Climate Change May Hamper Response to Flu: Study

    Previous studies have found that a warming climate may change the distribution of different diseases and the insects that carry them.
  • Two-Dose Rabies PEP Vaccine as Effective as Four-Dose Schedule

    A 2-dose single-visit intradermal postexposure prophylaxis (PEP) vaccine schedule was as immunologically effective and safe as a 4-dose single-visit intradermal PEP for rabies in healthy adults 7 to 28 months after 2-dose single-visit intradermal pre-exposure prophylaxis (PrEP).
  • Have vaccines become victims of their success?

    Science tells us that when you tell someone they’re wrong, they’re more likely to dig in than to experience a change of heart.
  • Metagenomic Sequencing of Viral Outbreak Reveals Transmission Clusters

    Real-time metagenomic sequencing identified genetically distinct, chronologically overlapping case clusters during a hospital-associated norovirus outbreak and further showed that after the epidemiologically defined outbreak had ceased, ongoing transmission and shedding of outbreak-associated virus occurred.
  • PEPFAR partners reveal HIV prevention service cuts from expanded “Mexico City Policy,” as organizati

    When the Trump administration State Department began to enforce a newly reinstated, and greatly expanded version of the restrictions on health information provided by U.S.-funded overseas organizations known as the “Mexico City Policy” the restrictions had never before been applied to the President’s Emergency Plan for AIDS Relief.
  • Algorithm Reduces Antibiotic Use in Lower Respiratory Tract Infection

    The duration of antibiotic regimens to treat lower respiratory tract infection can be reduced through the use of a procalcitonin-guided algorithm, according to a study published in Open Forum Infectious Diseases.
  • Shingles vaccine side effects mostly mild, yet 3% of complaints were serious, CDC says

    Reported side effects of the Shringrix shingles vaccine in its first eight months of doctors' office use were mostly unremarkable, but 3% of the complaints were serious, according to a Thursday report from the US Centers for Disease Control and Prevention.
  • Over 70,000 vaccinated against Ebola as outbreak marches on

    More than 70,000 people in the Democratic Republic of the Congo (DRC) have now been vaccinated with VSV-EBOV, Merck's unlicensed Ebola vaccine, according to today's update from DRC health officials.
  • Patients in Northwest measles outbreak traveled to Hawaii

    A measles outbreak in the Pacific Northwest became more worrisome Wednesday with word that people infected with the extremely contagious viral illness traveled to Hawaii and central Oregon after being exposed.
  • Rotavirus Vaccine May Protect Against Type 1 Diabetes

    The vaccine that prevents rotavirus, which can cause severe gastric problems in children, may have another benefit: lowering the risk for Type 1 diabetes in toddlers.
  • Anti-Vaccination Movement’s Purposeful Misinformation Is Categorically Wrong

    The State of Washington has declared an emergency because of a measles outbreak in Clark County, which is across the river from Portland, Oregon.
  • Takeda dengue vaccine meets main goal of trial; detailed results to come

    Takeda Pharmaceutical Co said on Tuesday that its experimental dengue vaccine appears to be safe and effective at preventing all four types of the mosquito-borne disease, meeting the main goal of the Japanese drugmaker’s late-stage clinical trial.
  • Officials urge vaccinations amid Northwest measles outbreak

    Public health officials scrambling to contain a measles outbreak in the U.S. Northwest warned people to vaccinate their children Monday and worried that it could take months to contain the highly contagious viral illness due to a lower-than-normal vaccination rate at the epicenter of the crisis.
  • As Ebola vaccinations begin in South Sudan, DRC officials highlight challenges, perceptions

    Vaccinations against Ebola in a South Sudan city close to the border of the Democratic Republic of Congo where the virus continues to spread, began today, the latest recognition of the potential for the ongoing war-zone outbreak still not officially deemed a Public Health Emergency of International Concern — or PHEIC — to become one.
  • Senators want update on progress of universal flu vaccine

    Maine’s independent U.S. senator says he’s joining a group of Senate colleagues to call on the National Institute of Allergy and Infectious Diseases to provide an update on research into a universal flu vaccine.
  • Monoclonal antibody Ebola treatment shown safe in adults

    As the Ebola outbreak in the Democratic Republic of the Congo (DRC) grew by six cases today, early data show that mAB114, a monoclonal antibody treatment for the disease, is safe and well-tolerated in adults, according to the results from the first human trial of the drug published today in The Lancet.
  • HIV-positive men more likely to develop lung disease from smoking marijuana, study says

    HIV-infected men who smoke marijuana for long periods of time are more likely to be diagnosed with lung disease, according to a study published Thursday by researchers at Dana-Farber Cancer Institute.
  • HIV-Positivity Not Associated With Higher Household Influenza Transmission

    Transmission of the seasonal influenza virus did not demonstrate a positive association with HIV-positive status despite the increased vulnerability to infection in individuals with HIV, according to a study recently published in the Journal of Infectious Diseases.
  • Planned Parenthood “Global Gag Rule” report is latest to diverge sharply from State Department asses

    Drawing on previously published findings and on-the-ground interviews, a report from Planned Parenthood details damage to global health gains, including in closed programs, weakened civil society, divided communities, and squandered local training, as well as direct impacts to public and individual health from the policy introduced by the Trump administration two years ago called “Protecting Life in Global Health Assistance.”
  • Bexsero Vaccine Has Potential for Cross-Protection Against Gonorrhea

    Meningococcal vaccine antigens may generate an immune response that recognizes gonococcal proteins, according to study findings published in Clinical Infectious Diseases.
  • Polio-Mozambique story

    In a story Jan. 22 about polio in Mozambique, The Associated Press reported erroneously the number of polio cases. There is one case, not two.
  • Merck to ship 120,000 more Ebola vaccine doses

    Drugmaker Merck says it will ship another approximately 120,000 doses of an experimental Ebola vaccine to Congo by the end of next month amid the second deadliest outbreak in history.
  • N.J. measles outbreak declared officially over after 33 confirmed cases

    More than two months after the first case of the measles was confirmed in New Jersey, officials say the outbreak has come to an end with 33 people infected.
  • More women catch Ebola in Congo in 'unexpected' twist of gender roles

    About two-thirds of patients in Congo’s latest Ebola outbreak have been women, the World Health Organization said on Thursday, calling for more focus on gender in disease control and prevention.
  • Shorter Antibiotic Course Noninferior for Gram-Negative Bacteremia

    A 7-day antibiotic course has demonstrated noninferiority compared with a 14-day course in treating uncomplicated gram-negative bacteremia, according to a study published in Clinical Infectious Diseases.
  • Metronidazole Successful for Mild C difficile in Patients Under 65

    Metronidazole and vancomycin showed similar results in initial mild C difficile infections in patients 65 years and older, according to a recent report.
  • FDA approves expanded use of Adacel (Tdap) vaccine for repeat vaccination

    Bridgewater-based Sanofi announced that the U.S. Food and Drug Administration has approved the expanded use of Adacel (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis (Tdap) Vaccine Adsorbed) to include repeat vaccination to help protect against tetanus, diphtheria and pertussis.
  • Giardiasis Linked With Prolonged Alteration of Lymphocytes in Duodenal Mucosa

    Chronic infection with Giardia was associated with prolonged alterations in duodenal mucosa lymphocytes.
  • In Syracuse, Schumer asks FDA to declare emergency for shingles vaccine

    U.S. Sen. Chuck Schumer has asked the Food and Drug Administration to declare an emergency in an effort to stock local pharmacies with a shingles vaccine, which is in short supply.
  • Incidence of Herpes Zoster Higher Among Women and Older Adults

    Herpes zoster virus continues to be prevalent in certain patient demographics in the United States, according to a study recently published in Clinical Infectious Diseases.
  • Indonesia seeks to reassure HIV patients over drug supplies

    Indonesia’s health ministry has sought to reassure HIV patients that sufficient antiretroviral (ARV) drugs will be available for their treatment after some hospitals had run out of supplies.
  • UK to double participation in trial of popular HIV prevention pill

    Health authorities in England said on Friday that they support a plan to double to 26,000 the number of participants in an HIV prevention pill trial, ahead of a potential national roll-out.
  • Severe Flu Raises Risk Of Birth Problems For Pregnant Women, Babies

    Need another reason to get the flu shot if you're pregnant?
  • Urokinase Plasminogen Receptor Levels Linked to Non-AIDS Related Events During ART Viral Suppression

    In patients with HIV, elevated levels of soluble urokinase plasminogen activator receptor are associated with non-AIDS events, according to study results published in Clinical Infectious Diseases.
  • Study sheds more light on delamanid role in treating MDR-TB

    A phase 3 trial of delamanid, a newer oral drug for treating multidrug-resistant tuberculosis (MDR-TB), found no statistically significant reduction in time to sputum culture conversion when compared to placebo, but that it was safe and well tolerated.
  • Kaposi's Sarcoma-Associated Herpes Virus Drives its Pathogenesis

    Patients with epidemic and endemic Kaposi Sarcoma (KS) have similar antibody and cytokine responses, suggesting that KS-associated herpes virus drives Kaposi Sarcoma pathogenesis, according to results published in the Journal of Infectious Diseases.
  • Deep Learning Algorithm Outperforms Physicians Detecting Active Pulmonary TB

    A deep-learning algorithm performed better than radiologists at detecting active pulmonary tuberculosis (TB) on chest radiographs, according to data published in Clinical Infectious Diseases.
  • Breast Milk Pasteurization Decreased Postnatal Cytomegalovirus

    The short-term pasteurization of breast milk from mothers with cytomegalovirus (CMV) significantly decreased CMV infections in very preterm infants, according to data published in Clinical Infectious Diseases.